4-FLUOROBENZALDEHYDE OXIME

  • CAS:588-95-4
  • purity:99%
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Details

Reliable factory customized supply 4-FLUOROBENZALDEHYDE OXIME 588-95-4

  • Molecular Formula: C7H6FNO
  • Molecular Weight: 139.129
  • Melting Point: 82-85 °C (lit.) 
  • Boiling Point: 194.9 °C at 760 mmHg 
  • PKA: 11.18±0.10(Predicted) 
  • Flash Point: 71.7 °C 
  • PSA: 32.59000 
  • Density: 1.14 g/cm3 
  • LogP: 1.63380 

4-FLUOROBENZALDEHYDE OXIME(Cas 588-95-4) Usage

General Description

4-Fluorobenzaldehyde oxime is a chemical compound that is derived from fluorobenzaldehyde and hydroxylamine. It is commonly used as a reagent in organic synthesis and as a building block in the production of various pharmaceuticals and agrochemicals. 4-FLUOROBENZALDEHYDE OXIME has a wide range of applications, including as an intermediate in the synthesis of dyes, perfumes, and other organic compounds. It also exhibits potential for use in medicinal chemistry, particularly in the development of inhibitors for certain enzymes and receptors. Additionally, its properties make it suitable for use as a chelating agent in metal extraction processes and as a reagent in analytical chemistry. Overall, 4-Fluorobenzaldehyde oxime is a versatile compound with diverse uses in both the industrial and research sectors.

InChI:InChI=1/C7H6FNO/c8-7-3-1-6(2-4-7)5-9-10/h1-5,10H/b9-5+

588-95-4 Relevant articles

Visible-light mediated stereospecific C(sp2)-H difluoroalkylation of (Z)-aldoximes

Chen, Hua,Deng, Hongmei,Gong, Haiying,Hao, Jian,Li, Mingjie,Peng, Yi,Wan, Wen,Wang, Qian,Zhang, Yifang

supporting information, p. 7867 - 7874 (2021/09/28)

A visible light mediated stereospecific ...

Water mediated procedure for preparation of stereoselective oximes as inhibitors of MRCK kinase

Luqman, Suaib,Misra, Krishna,Pandey, Jyoti,Shrivash, Manoj Kumar,Shukla, Akhilesh Kumar,Singh, Shilipi

, (2020/07/08)

Stereoselective aldoximes, preferably Z ...

ISOXAZOLO-PYRIDAZINE DERIVATIVES

-

, (2009/06/27)

The invention relates to isoxazolo-pyrid...

(E)-Phenyl- and -heteroaryl-substituted O-benzoyl-(or acyl)oximes as lipoprotein-associated phospholipase A2 inhibitors

Jeong, Tae-Sook,Kim, Mi Jeong,Yu, Hana,Kim, Kyung Soon,Choi, Joong-Kwon,Kim, Sung-Soo,Lee, Woo Song

, p. 1525 - 1527 (2007/10/03)

A series of (E)-phenyl- and -heteroaryl-...

588-95-4 Process route

ethyl (E)-2-cyano-3-(4-fluorophenyl)-2-propenoate
18861-57-9,50737-52-5

ethyl (E)-2-cyano-3-(4-fluorophenyl)-2-propenoate

syn-4-fluorobenzaldoxime
588-95-4,7304-35-0

syn-4-fluorobenzaldoxime

Conditions
Conditions Yield
With hydroxylamine hydrochloride; sodium carbonate; In methanol; water; at 100 ℃; for 1h; stereoselective reaction;
92%
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

syn-4-fluorobenzaldoxime
588-95-4,7304-35-0

syn-4-fluorobenzaldoxime

Conditions
Conditions Yield
84%
84%
With hydroxylamine hydrochloride; sodium acetate; In methanol; water; at 20 ℃; for 12h; stereoselective reaction;
82%
With hydroxylamine hydrochloride; sodium carbonate;
Multi-step reaction with 2 steps
2: benzene; HCl
With hydrogenchloride; benzene;
With sodium hydroxide; hydroxylamine hydrochloride; In ethanol;
Multi-step reaction with 2 steps
1: piperidine / ethanol / 80 - 85 °C
2: sodium carbonate; hydroxylamine hydrochloride / water; methanol / 1 h / 100 °C
With piperidine; hydroxylamine hydrochloride; sodium carbonate; In methanol; ethanol; water;

588-95-4 Upstream products

  • 459-23-4
    459-23-4

    (E)-4-fluorobenzaldehyde oxime

  • 459-57-4
    459-57-4

    4-fluorobenzaldehyde

  • 18861-57-9
    18861-57-9

    ethyl (E)-2-cyano-3-(4-fluorophenyl)-2-propenoate

588-95-4 Downstream products

  • 459-23-4
    459-23-4

    (E)-4-fluorobenzaldehyde oxime

  • 1194-02-1
    1194-02-1

    4-fluorobenzonitrile

  • 753479-66-2
    753479-66-2

    [3-(4-fluorophenyl)isoxazol-5-yl]methyl acetate

  • 393165-20-3
    393165-20-3

    (Z)-N-hydroxy-4-fluoro-benzenecarboximidoyl chloride