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Details
Offer Chemical Raw Material ETHYL 3-HYDROXYHEXANOATE 2305-25-1 In Stock
- Molecular Formula: C8H16O3
- Molecular Weight: 160.213
- Vapor Pressure: 0.00608mmHg at 25°C
- Refractive Index: n20/D 1.428(lit.)
- Boiling Point: 241.7 °C at 760 mmHg
- PKA: 14.45±0.20(Predicted)
- Flash Point: 94.4 °C
- PSA： 46.53000
- Density: 0.989 g/cm3
- LogP: 1.10060
ETHYL 3-HYDROXYHEXANOATE(Cas 2305-25-1) Usage
|
Synthesis Reference(s) |
The Journal of Organic Chemistry, 39, p. 269, 1974 DOI: 10.1021/jo00916a043 |
|
Definition |
ChEBI: A fatty acid ester that is the ethyl ester of 3-hydroxyhexanoic acid. |
|
Taste threshold values |
Taste characteristics at 80 ppm: sweet, fruity, grape with citrus notes. |
InChI:InChI=1/C8H16O3/c1-3-5-7(9)6-8(10)11-4-2/h7,9H,3-6H2,1-2H3/t7-/m0/s1
2305-25-1 Relevant articles
Organic Sonochemistry. Sonic Acceleration of the Reformatsky Reaction
Han, Byung-Hee,Boudjouk, Philip
, p. 5030 - 5032 (1982)
-
Synthesis method of ethyl 3-hydroxyhexanoate
-
Paragraph 0017; 0020; 0021; 0024; 0025; 0028; 0029; 0032, (2020/02/27)
The invention discloses a synthesis meth...
Efficient asymmetric synthesis of chiral alcohols using high 2-propanol tolerance alcohol dehydrogenase: Sm ADH2 via an environmentally friendly TBCR system
Yang, Zeyu,Fu, Hengwei,Ye, Wenjie,Xie, Youyu,Liu, Qinghai,Wang, Hualei,Wei, Dongzhi
, p. 70 - 78 (2020/01/21)
Alcohol dehydrogenases (ADHs) together w...
Synthesis of Long-Chain β-Lactones and Their Antibacterial Activities against Pathogenic Mycobacteria
Santucci, Pierre,Dedaki, Christina,Athanasoulis, Alexandros,Gallorini, Laura,Munoz, Ana?s,Canaan, Stéphane,Cavalier, Jean-Fran?ois,Magrioti, Victoria
supporting information, p. 349 - 358 (2019/01/25)
In the quest for new antibacterial agent...
Synthesis of Thelepamide via Catalyst-Controlled 1,4-Addition of Cysteine Derivatives and Structure Revision of Thelepamide
Seitz, Tobias,Millán, Ramón E.,Lentz, Dieter,Jiménez, Carlos,Rodríguez, Jaime,Christmann, Mathias
supporting information, p. 594 - 597 (2018/02/10)
The first enantioselective total synthes...
2305-25-1 Process route
-
-
123-72-8
butyraldehyde
-
-
105-36-2
ethyl bromoacetate
-
-
2305-25-1
3-hydroxy-hexanoic acid ethyl ester
| Conditions | Yield |
|---|---|
|
With
indium;
In
tetrahydrofuran;
at 20 ℃;
for 3h;
ultrasonic cleaner bath (43 kHz wave; power 435 W);
|
95%
|
|
With
iodine; zinc;
In
1,4-dioxane;
for 0.0833333h;
Irradiation;
|
91%
|
|
With
iodine; zinc;
In
1,4-dioxane;
at 25 - 30 ℃;
for 0.0833333h;
Product distribution;
Irradiation;
other promoter, KI; other aldehydes and ketones;
|
90%
|
|
With
zinc;
In
tetrahydrofuran;
at 66 ℃;
for 0.0166667h;
|
90%
|
|
With
manganese;
bis(cyclopentadienyl)titanium dichloride;
In
tetrahydrofuran;
at 20 ℃;
|
78%
|
|
With
chloro-trimethyl-silane; zinc;
In
diethyl ether;
for 1h;
Heating;
|
70%
|
|
With
zinc;
In
benzene;
for 0.5h;
Heating;
|
31%
|
|
With
zinc;
In
diethyl ether; benzene;
for 2.5h;
Heating;
|
20%
|
|
With
zinc; benzene;
|
|
|
With
zinc;
In
benzene;
|
|
|
With
zinc;
|
|
|
In
dichloromethane;
for 5h;
Reflux;
|
-
-
3249-68-1
ethyl butyroyl acetate
-
-
2305-25-1
3-hydroxy-hexanoic acid ethyl ester
| Conditions | Yield |
|---|---|
|
With
sodium tetrahydroborate;
In
ethanol;
at 0 - 10 ℃;
for 0.5h;
|
85%
|
|
With
sodium tetrahydroborate;
In
ethanol;
at 20 ℃;
|
81%
|
|
With
hydrogen;
nickel;
In
ethanol;
|
|
|
With
hydrogen; 1-butyl-3-methylimidazolium Tetrafluoroborate;
rac-Ru-BINAP;
In
methanol;
at 20 ℃;
for 22h;
under 77574.3 Torr;
|
|
|
With
sodium tetrahydroborate;
|
2305-25-1 Upstream products
-
123-72-8
butyraldehyde
-
105-36-2
ethyl bromoacetate
-
927-80-0
1-ethoxyacetylene
-
3249-68-1
ethyl butyroyl acetate
2305-25-1 Downstream products
-
412299-21-9
ethyl 4-hydroxy-2-propyl-5-oxo-2,5-dihydrofuran-3-carboxylate
-
345922-13-6
5-hydroxy-3-oxo-2-(triphenyl-λ5 -phosphanylidene)-octanenitrile
-
345922-12-5
acetic acid 4-cyano-3-oxo-1-propyl-4-(triphenyl-λ5 -phosphanylidene)-butyl ester
-
345922-11-4
5-(tert -butyl-dimethyl-silanyloxy)-3-oxo-2-(triphenyl-λ5 -phosphanylidene)-octanenitrile
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