2-Acetoxy-4-trifluoromethylbenzoic acid

  • CAS:322-79-2
  • purity:99%
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What is the 2-Acetoxy-4-trifluoromethylbenzoic acid ?

2-Acetoxy-4-trifluoromethylbenzoic acid is , while it's Molecular Formula is C10H7F3O4. Antithrombotic;Cyclooxygenase inhibitor

What is the CAS number for 2-Acetoxy-4-trifluoromethylbenzoic acid ?

The CAS number of 2-Acetoxy-4-trifluoromethylbenzoic acid is 322-79-2.

More information of 2-Acetoxy-4-trifluoromethylbenzoic acid 322-79-2 are:

Synonyms

2,4-Cresoticacid, a,a,a-trifluoro-, acetate (7CI,8CI);2-Acetoxy-4-(trifluoromethyl)benzoic acid;2-Carboxy-5-(trifluoromethyl)phenyl acetate;Disgren;UR 1501;

CAS?Number

322-79-2

Molecular Formula

C10H7F3O4

Molecular Weight

248.158

Density

1.433 g/cm3

Melting Point

120-122° (upon slow heating); 110-112° (upon quick heating)

Boiling Point

316 °C at 760 mmHg

Flash Point

144.9 °C

Pka

2.97±0.10(Predicted)

What is 2-Acetoxy-4-trifluoromethylbenzoic acid (322-79-2) used for?

Triflusal is an antiplatelet agent structurally related to the salicylates, but it is not derived from ASA. Triflusal and its metabolite (3-hydroxy-4-triuoro-methylbenzoic acid or HTB) produce specic inhibition of platelet arachidonic acid metabolism (McNeely and Goa, 1998). A single 12-month open-label trial of Triflusal in 73 VaD patients (López-Pousa et al., 1997) showed fewer declines in MMSE scores in the active group compared with untreated subjects. More recently, Triflusal was used in patients with amnesic MCI; 257 patients were randomized to receive 900 mg of Triflusal or placebo for 18 months. Triflusal therapy was associated with a signicantly lower rate of conversion to dementia (Gómez-Isla et al., 2008).

InChI:InChI=1/C10H7F3O4/c1-5(14)17-8-4-6(10(11,12)13)2-3-7(8)9(15)16/h2-4H,1H3,(H,15,16)

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